Research and Publications

Peer-reviewed articles, conference papers, and scientific collaborations showcasing the research behind our innovations.

November 17, 2025

Di Liddo R, Naso F, Gandaglia A, Sturaro G, Spina M, Melder R.J. Enhanced Detection of αGal Using a Novel Monoclonal IgG1 Antibody: Comparative Evaluation with IgM Antibody [Clone M86]. J. Pers. Med. 2025, 15, 558. https://doi.org/10.3390/jpm15110558

May 10, 2024

Naso F, Gandaglia A, Sturaro G, Galli C, Melder RJ. The α-Gal KO Mouse Animal Model is a Reliable and Predictive Tool for the Immune-Mediated Calcification Assessment of Heart Valve Bioprostheses. Front Biosci (Landmark Ed). 2024 May 10;29(5):181. doi: 10.31083/j.fbl2905181. PMID: 38812319.

June 21, 2023

Naso F, Colli A, Zilla P , Calafiore AM, Lotan C, Padalino MA, Sturaro G, Gandaglia A, Spina M. Correlations between the alpha-Gal antigen, antibody response and calcification of cardiac valve bioprostheses: experimental evidence obtained using an alpha-Gal knockout mouse animal model. Front Immunol. 2023 Jun 21;14:1210098. doi: 10.3389/fimmu.2023.1210098. PMID: 37426661; PMCID: PMC10327888.

April 3, 2023

Melder RJ, Naso F, Nicotra F, Russo L, Vesely I, Tuladhar SR, Calafiore AM, Zilla P, Gandaglia A, Korossis S. Preventing extrinsic mechanisms of bioprosthetic degeneration using polyphenols. Eur J Cardiothorac Surg. 2023 Apr 3;63(4):ezac583. doi: 10.1093/ejcts/ezac583. PMID: 36548449.

September 30, 2022

Naso F, Calafiore AM, Gaudino M, Zilla P, Haverich A, Colli A, Melder RJ, Gandaglia A. Polyphenols could be Effective in Exerting a Disinfectant-Like Action on Bioprosthetic Heart Valves, Counteracting Bacterial Adhesiveness. Cardiol Cardiovasc Med. 2022;6(5):487-492. doi: 10.26502/fccm.92920287. Epub 2022 Sep 30. PMID: 36303878; PMCID:PMC9601395.

June 9, 2021

Angiolillo A, Gandaglia A, Arcaro A, Carpi A, Gentile F, Naso F, Di Costanzo A. Altered Blood Levels of Anti-Gal Antibodies in Alzheimer's Disease: A New Clue to Pathogenesis? Life (Basel). 2021 Jun 9;11(6):538. doi: 10.3390/life11060538. PMID: 34207559; PMCID: PMC8228012.

October 22, 2017

Naso F, Gandaglia A. Different approaches to heart valve decellularization: A comprehensive overview of the past 30 years. Xenotransplantation. 2018 Jan;25(1). doi:10.1111/xen.12354. Epub 2017 Oct 22. PMID: 29057501.

October 19, 2017

Naso F, Stefanelli U, Buratto E, Lazzari G, Perota A, Galli C, Gandaglia A. Alpha-Gal Inactivated Heart Valve Bioprostheses Exhibit an Anti-Calcification Propensity Similar to Knockout Tissues. Tissue Eng Part A. 2017 Oct;23(19-20):1181-1195. doi: 10.1089/ten.tea.2016.0474. Epub 2017 Jun 21. PMID: 29053434.